Explore our current projects at the Applied Physiology and Advanced Imaging (APAI) Laboratory, a hub of innovation dedicated to addressing critical cardiovascular health issues.

Within this page, you’ll discover our extensive range of research initiatives, from cutting-edge cardiac imaging techniques to groundbreaking studies in vascular function. Our collaborations with leading experts and institutions are driving forward our understanding of complex health conditions like heart failure and the nuanced effects of various therapies.

By joining forces with us as a research volunteer, you have the opportunity to be part of these transformative projects, contributing significantly to the advancement of cardiovascular health and patient care.

Interested in being a research volunteer in the APAI Lab? Fill out our interest form.


Cardiac Imaging

  • Mechanisms of Exercise Intolerance in Heart Failure with Preserved Ejection Fraction: ‘Precision’ Therapy Based on Patient Specific Pathophysiology
    • In collaboration with The Institute of Exercise and Environmental Medicine
  • Partitioning the cardiometabolic effects of antiretroviral therapy from human immunodeficiency virus.
  • FUVID Study: Functional Characterization of Children with Chronic Venous Thromboembolic Disease
    • In collaboration with Dr. Ayesha Zia at Children’s Hospital Dallas
  • Diastolic Dysfunction in Women with Ischemia but no Obstructive Coronary Artery Disease
    • In collaboration with Dr. C. Noel Bairey Merz at Cedars-Sinai Medical Center, Los Angeles
  • Impact of Myocardial Lipid Composition of Left Ventricular Morphology and Function
    • In collaboration with The Dallas Heart Study and UT Southwestern Medical Center
  • Cardiac Stress Imaging Development and Application
  • Mechanism and Modulation of Sex Differences in Myocardial Steatosis Induced Left Ventricular Dysfunction
  • Identifying Subclinical Transthyretin Cardiac Amyloidosis in Asymptomatic Carriers of the V122I TTR Allele
    • In collaboration with Dr. Justin Grodin at UT Southwestern Medical Center

Vascular Function and Muscle Metabolism

  • Improving prognosis and diagnosis in Peripheral Artery Disease with Diffuse Correlation Spectroscopy
  • Development and application of Near Infrared Diffuse Correlation Spectroscopy to study the determinants of skeletal muscle oxygen utilization